Lilemong tsa morao tjena, hyperbaric oxygen therapy (HBOT) e hlahile e le mokhoa oa ho thibela le ho phekola mafu a pelo. Phekolo e sebelisa molao-motheo oa "phepelo ea oksijene 'meleng" ho fana ka ts'ehetso ea bohlokoa ho pelo le boko. Ka tlaase mona, re hlahloba melemo ea mantlha ea HBOT, haholo-holo mabapi le ho rarolla mathata a amanang le boemo ba ischemic myocardial.
Ho Lokolla Matla a Phepelo ea Oksijene ea 'Mele
Lipatlisiso li bontša hore ka har'a kamore ea hyperbaric ho 2 atmospheres ea khatello (hyperbaric chamber 2 ata), ho qhibiliha ha oksijene ho feta makhetlo a leshome ho feta khatello e tloaelehileng. Ho monya hona ho matlafalitsoeng ho etsa hore oksijene e kenelle libakeng tse sitisang phallo ea mali, 'me e qetelle e isa "oksijene ea tšohanyetso" pelong ea ischemic kapa lisele tsa boko. Mochine ona o ipaka o le molemo haholo ho batho ba nang le hypoxia e sa foleng ka lebaka la maemo a kang coronary artery stenosis le cerebral arteriosclerosis, a fanang ka phomolo e potlakileng matšoao a kang ho tiea sefuba le ho tsekela.
Ho khothaletsa Angiogenesisle Ho Aha Secha Mecha ea Oksijene
Phekolo ea oksijene ea hyperbaric ha e sebetsane le litlhoko tse potlakileng feela empa e boetse e khothalletsa ho hlaphoheloa ha nako e telele ka ho susumetsa ho lokolloa ha vascular endothelial growth factor (VEGF). Ts'ebetso ena e thusa ho theha phallo ea mali libakeng tsa ischemic, e ntlafatsa haholo phepelo ea mali ho pelo le boko. Liphuputso li bontšitse hore ka mor'a mananeo a 20 a HBOT, bakuli ba lefu la methapo ea pelo ba ile ba bona keketseho e tsotehang ea microcirculation ea myocardial ka 30% ho isa ho 50%.
Anti-inflammatory le Antioxidant Effects: Ho Sireletsa Mosebetsi oa Cell
Ntle le bokhoni ba eona ba oksijene, HBOT e na le litlamorao tse khahlanong le ho ruruha le li-antioxidant, e etsa hore e be bohlokoa bakeng sa ho sireletsa pelo le tšebetso ea lisele tsa boko. Lipatlisiso li bontša hore phekolo e ka hatella litsela tsa ho ruruha tse kang NF-κB, ho fokotsa ho lokolloa ha lintho tse thibelang ho ruruha tse kang TNF-α le IL-6. Ho feta moo, ntlafatso ea ts'ebetso ea superoxide dismutase (SOD) e thusa ho felisa li-radicals tsa mahala, ho fokotsa tšenyo ea endothelial le ho fana ka ts'ireletso khahlanong le maemo a sa foleng a ho ruruha joalo ka atherosclerosis le liphetoho tse amanang le lefu la tsoekere.
Lits'ebetso tsa Clinical tsa Hyperbaric Oxygen ho Mafu a pelo
Liketsahalo tse Hloahloa tsa Ischemic
Myocardial Infarction: Ha e sebelisoa hammoho le thrombolysis kapa mekhoa ea phekolo ea ho kenella, HBOT e ka atleha ho fokotsa apoptosis ea lisele tsa myocardial le ho fokotsa kotsi ea ho ba le li-arrhythmias tse kotsi.
Cerebral Infarction: Tšebeliso ea pele ea phekolo ea oksijene ea hyperbaric e ka lelefatsa ho phela ha lisele, ho fokotsa boholo ba infarct, le ho ntlafatsa ts'ebetso ea methapo.
Ho Tsosolosa Mafu a sa Feleng
Lefu le tsitsitseng la Coronary Artery: Hangata bakuli ba na le matšoao a ntlafetseng a angina, ho mamella ho ikoetlisa ho eketsehileng, le ho fokotsa ho itšetleha ka meriana ea nitrate.
Rapid Atrial Arrhythmias (Mofuta o Butle): Ka liphello tse mpe tsa inotropic, HBOT e thusa ho fokotsa lebelo la pelo, ho fokotsa tšebeliso ea oksijene ea myocardial, le ho ntlafatsa maemo a ischemic.
Boloetse ba Pelo ea Hypertensive: Phekolo e fokotsa sekhahla sa mali le ho fokotsa hypertrophy ea ventricular e ka letsohong le letšehali, ka katleho e liehisa tsoelo-pele ea ho hloleha ha pelo.
Post-Stroke Sequelae: Lithuso tsa HBOT tokisong ea synaptic, ho ntlafatsa ts'ebetso ea makoloi le bokhoni ba kelello.
Tlaleho ea Tšireletso ea Hyperbaric Oxygen Therapy
HBOT ka kakaretso e nkuoa e bolokehile, e na le litla-morao tse fokolang. Matšoenyeho a mantlha hangata ke khatello e tlase ea tsebe, e ka fokotsoang ka ho lokisa khatello. Leha ho le joalo, ho na le li-contraindications tse itseng, tse kenyelletsang ho tsoa mali ka mafolofolo, pneumothorax e sa phekoloeng, emphysema e matla, pulmonary bullae, le thibelo e feletseng ea pelo.
Ditebello tsa Bokamoso: Ho Tloha ka Kalafo ho ya Thibelong
Lipatlisiso tse ntseng li hlaha li totobatsa bokhoni ba HBOT ba ho liehisa ts'ebetso ea atherosclerotic ka ho ntlafatsa vascularityity le ho theola maemo a lipids maling. Sena se beha oksijene ea hyperbaric e le mokhoa o sebetsang oa ho loants'a "hypoxia e khutsitseng," haholo-holo ho batho ba nang le matšoao a kang ho tsekela, ho fokotseha ha mohopolo le ho hlobaela. Ka tsoelopele ea ntlafatso ea kalafo e thusoang ke AI le lits'ebetso tse ncha tse kang stem cell therapy, HBOT e kanna ea ba mothating oa ho ba motheo oa taolo ea bophelo bo botle ba pelo.
Qetello
Phekolo ea oksijene ea hyperbaric e hlahella e le tharollo e tšepisang, e seng ea meriana bakeng sa mafu a pelo, e hahiloeng motheong oa "phepelo ea oksijene ea 'mele." Mokhoa ona o nang le mefuta e mengata, o kopanyang ho lokisoa ha methapo, litlamorao tse khahlanong le ho ruruha, le melemo ea antioxidant, e bonts'a melemo e mengata maemong a tšohanyetso a hlobaetsang le ho tsosolosoa ho sa foleng. Ho feta moo, tšebeliso ea electrocardiograms (ECG) e le pontšo e hlokolosi ea oksijene le ischemia e ka sebetsa e le bopaki ba bohlokoa ba kliniki bo tšehetsang katleho ea HBOT. Ho khetha HBOT ha se ho khetha phekolo feela; e bolela boitlamo ba ho laola bophelo bo botle le boiketlo ba motho.
Nako ea poso: Apr-30-2025